Make sure needle-free neffy® (epinephrine nasal spray) is on your back-to-school checklist this year

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Back-to-school means more than pencils and planners for families managing allergic reactions

As backpacks fill and routines ramp up, so does the need to be prepared, not just with school supplies, but in case of accidental allergen exposure.

Now, there’s a way to do that without a needle. Meet neffy® (epinephrine nasal spray).

What makes neffy different?

neffy is the only needle-free epinephrine nasal spray, no more injections! If an allergic reaction happens at school, practice, or on-the-go, neffy starts to work in under a minute, providing fast, trusted epinephrine that your child needs. neffy is designed to be easy to use, so teachers, coaches, and others can step in to help quickly and without hesitation—even if you’re not with your child.

Designed for the pace of everyday life, neffy fits into the moments that matter.

neffy supports children who fear injections, others who may hesitate, and caregivers who know how critical timing can be.

neffy may cause side effects so it’s important to talk to a doctor about any medical conditions or medications to determine if neffy is the right option.

Want to know more about neffy?

Why should you put neffy on your back-to-school checklist?

neffy’s innovative needle-free design sets it apart. But that’s not all that makes neffy special. 

neffy:

  • Supports your child as they grow
    • neffy 1 mg for those 4 years and older who weigh 33 to less than 66 lbs
    • neffy 2 mg for those who weigh 66 lbs and greater
  • Is about the size of a car key and fits easily into backpacks, lunchboxes, fanny packs, as well as your school day routine
  • Has a longer shelf life than needle-injectors—2 years for 1 mg*, 2.5 years for 2 mg* 
  • Is temperature tolerant up to 122°F for a few days, no special accommodations needed. Simply store neffy at room temperature between 68°F to 77°F
    Do not freeze. If neffy freezes, the device will not spray.
    *From date of manufacture.

Watch how to use neffy

Hear from a real neffy mom

Take the next step with neffy

neffy is available through many insurance plans. Pay as little as $25 for neffy through the Co-Pay Savings Program. Get at least 4 devices for $25, if eligible. Ask your doctor to prescribe 2 or more sets of neffy—for home, school, and for the backpack and locker.

Refill every 30 days or immediately after use to stay stocked and ready.

For commercial insurance only. See full terms and conditions. 

Find out more about Savings & Coverage

Hello school year. Goodbye needle fear.
Ask your child’s doctor for neffy.


INDICATION AND IMPORTANT SAFETY INFORMATION

WHAT IS neffy?

neffy is a nasal spray used for emergency treatment of allergic reactions including anaphylaxis, in adults and children aged 4 years and older who weigh 33 lbs or greater.

IMPORTANT SAFETY INFORMATION

What is the most important information that I should know about neffy?

neffy contains epinephrine, a medicine used to treat allergic emergencies (anaphylaxis). Anaphylaxis can be life-threatening, can happen in minutes, and can be caused by stinging and biting insects, allergy injections, foods, medicines, exercise, or other unknown causes.

Always carry two neffy nasal sprays with you because you may not know when anaphylaxis may happen and because you may need a second dose of neffy if symptoms continue or come back. Each neffy contains a single dose of epinephrine. neffy is for use in the nose only.

Use neffy right away, as soon as you notice symptoms of an allergic reaction. If symptoms continue or get worse after the first dose of neffy, a second dose is needed. If needed, administer a second dose using a new neffy in the same nostril starting 5 minutes after the first dose. Get emergency medical help for further treatment of the allergic emergency (anaphylaxis), if needed after using neffy.

Tell your healthcare provider if you have underlying structural or anatomical nasal conditions, about all the medicines you take, and about all your medical conditions, especially if you have heart problems, kidney problems, low potassium in your blood, Parkinson’s disease, thyroid problems, high blood pressure, diabetes, are pregnant or plan to become pregnant, or plan to breastfeed.

Tell your healthcare provider if you take or use other nasal sprays or water pills (diuretics) or if you take medicines to treat depression, abnormal heart beats, Parkinson’s disease, heart disease, thyroid disease, medicines used in labor, and medicines to treat allergies. neffy and other medications may affect each other, causing side effects. neffy may affect the way other medicines work, and other medicines may affect how neffy works.

What are the side effects of neffy?

neffy may cause serious side effects. If you have certain medical conditions or take certain medicines, your condition may get worse, or you may have more or longer lasting side effects when you use neffy.

Common side effects of neffy include: nasal discomfort, headache, throat irritation, chest and nasal congestion, feeling overly excited, nervous or anxious, nose bleed, nose pain, sneezing, runny nose, dry nose or throat, tingling sensation, including in the nose, feeling tired, dizziness, nausea, and vomiting.

Tell your healthcare provider if you have any side effects that bother you or that do not go away after using neffy.

These are not all of the possible side effects of neffy. Call your healthcare provider for medical advice about side effects. To report side effects, contact ARS Pharmaceuticals Operations, Inc. at 1-877-MY-NEFFY (877-696-3339)or the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please see the full Prescribing Information and Patient Information for neffy.

©2025 ARS Pharmaceuticals Operations, Inc. All rights reserved. “ARS Pharma,” the ARS Pharma logo design, “neffy,” and the neffy logo are trademarks or registered trademarks of ARS Pharmaceuticals Operations, Inc. All other trademarks are the property of their respective owners. NEF-US-0721 | 08/2025

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