Zeneo: A Needle-Free Epinephrine Auto-Injector Currently in Development


Crossject, a pharma company based in Dijon, France, is developing a needleless auto-injector device the company will use to deliver a portfolio of drugs including epinephrine.

The device consists of a specially designed glass tube that can withstand high pressure in combination with a propellant based on a nitrocellulose chemical reaction.

When activated, the device propels the drug under high pressure through the skin into the bloodstream without the need for a needle.

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The company website provides the following description:

In a validation study, ZENEO® demonstrated its ability to ensure correct intramuscular injection regardless of the amount of fat underneath the skin. Thus, ZENEO® is the only system to offer full performance regardless of patient morphology.

Also, ZENEO® eliminates phobias and handling errors associated with classic needle-based auto-injectors.

The administration of the device requires two steps:

  1. Removal of the safety cap, which automatically breaks the sterility seal.
  2. Perpendicular placement of the device on the skin surface and a push; a click signal occurs once the injection is completed (in less than a tenth of a second).
Zeneo Administration

We will follow up with Crossject to learn more about Zeneo and their timeline for introduction in the US.

Source: ZENEO, a unique device worldwide — Crossject Website
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Dave Bloom
Dave Bloom
Dave Bloom is CEO and "Blogger in Chief" of SnackSafely.com.

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